Research workbench
Crystal structure of truncated hemoglobin from tetrahymena pyriformis, Q50E mutant, FE(III) form
Analyse Crystal structure of truncated hemoglobin from tetrahymena pyriformis, Q50E… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3AQ9
- Type
- protein
- Length
- 234 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Group 1 truncated hemoglobin
- UniProt
- P17724
- Ligands
- HEM
- Pockets
- 2 · best druggability 0.74
Structure
x-ray diffraction · 1 distinct chain · 66% helix, 2% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Group 1 truncated hemoglobin | protein | 117 | 66% helix, 2% strand | P17724 |
Ligands and binding sites
- HEM · Protoporphyrin IX containing Fe · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 233 | 0.74 | 0.88 | 31 | HEM |
| 2 | 254 | 0.74 | 0.87 | 31 | HEM |
Interfaces
1 interface between chains.
- A–B · 667 Ų buried · 9 hydrogen bonds · protein-protein
Compared structures
- 3AQ9 · Crystal structure of truncated hemoglobin from Tetrahymena pyriformis, Q50E mutant… · the same entry in another collection · chain A against A, TM-score 1.00
- P17724 · AlphaFold monomer V2.0 prediction for group 1 truncated hemoglobin (P17724) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P17724
- Elsewhere: RCSB PDB 3AQ9 · PDBe 3AQ9 · UniProt P17724
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