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Crystal structure of yeast RPN14, a chaperone of the 19S regulatory particle of the proteasome

Analyse Crystal structure of yeast RPN14, a chaperone of the 19S regulatory particle of… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3ACP
Type: protein
Length: 417 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Wd repeat-containing protein YGL004C
UniProt: P53196
Pockets: 4 · best druggability 0.70

Structure

x-ray diffraction · 1 distinct chain · 1% helix, 50% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Wd repeat-containing protein YGL004C	protein	417	1% helix, 50% strand	P53196

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	688	0.70	0.77	58	empty
2	65	0.35	0.77	18	empty
3	84	0.35	0.75	20	empty
4	62	0.30	0.75	16	empty

Compared structures

3ACP · Crystal Structure of Yeast Rpn14, a Chaperone of the 19S Regulatory Particle of the… · the same entry in another collection · chain A against A, TM-score 1.00
P53196 · AlphaFold monomer V2.0 prediction for 26S proteasome regulatory subunit RPN14 (P53196) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P53196
Elsewhere: RCSB PDB 3ACP · PDBe 3ACP · UniProt P53196

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