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Small heat shock protein HSP14.0 with the mutations of I120F and I122F in the form II crystal

Analyse Small heat shock protein HSP14.0 with the mutations of I120F and I122F in the… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3AAC
Type: protein
Length: 244 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Putative uncharacterized protein ST1653
UniProt: Q970D9
Pockets: 3 · best druggability 0.41

Structure

x-ray diffraction · 2 distinct chains · 18% helix, 40% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Putative uncharacterized protein ST1653	protein	123	17% helix, 39% strand	Q970D9
B	Putative uncharacterized protein ST1653	protein	121	19% helix, 40% strand	Q970D9

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	102	0.41	0.77	25	empty
2	77	0.31	0.73	17	empty
3	54	0.29	0.75	14	empty

Interfaces

1 interface between chains.

A–B · 1591 Å² buried · 46 hydrogen bonds · protein-protein

Compared structures

3AAC · Small heat shock protein hsp14.0 with the mutations of I120F and I122F in the form II… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q970D9
Elsewhere: RCSB PDB 3AAC · PDBe 3AAC · UniProt Q970D9

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