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3'-DNA-RNA-5' junction formed during initiation of minus- strand synthesis of HIV replication

Analyse 3'-DNA-RNA-5' junction formed during initiation of minus- strand synthesis of… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
398D
Type
RNA
Length
32 nucleotides
Chains
4
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
RNA (5'-R(*GP*CP*AP*GP*UP*GP*GP*C)-3'); DNA/RNA (5'-R(*GP*CP*CP*AP)-D(*CP*TP*GP*C)-3')

Structure

x-ray diffraction · 2 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A, CRNA (5'-R(*GP*CP*AP*GP*UP*GP*GP*C)-3')rna8——
B, DDNA/RNA (5'-R(*GP*CP*CP*AP)-D(*CP*TP*GP*C)-3')rna8——

Interfaces

5 interfaces between chains.

  • A–B · 387 Ų buried · 36 hydrogen bonds · nucleic-nucleic
  • C–D · 385 Ų buried · 33 hydrogen bonds · nucleic-nucleic
  • A–C · 86 Ų buried · 3 hydrogen bonds · nucleic-nucleic
  • B–D · 84 Ų buried · 3 hydrogen bonds · nucleic-nucleic
  • B–C · 82 Ų buried · 2 hydrogen bonds · nucleic-nucleic

Compared structures

  • 398D · 3'-DNA-RNA-5' junction formed during initiation of minus-strand synthesis of HIV… · the same entry in another collection · chain A against A, TM-score 1.00

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