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Crystal structure of recj from thermus thermophilus HB8

Analyse Crystal structure of recj from thermus thermophilus HB8 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2ZXO
Type: protein
Length: 648 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Single-stranded DNA specific exonuclease recj
EC: 3.1.11.-
UniProt: Q5SJ47
Pockets: 5 · best druggability 0.70

Structure

x-ray diffraction · 1 distinct chain · 42% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Single-stranded DNA specific exonuclease recj (EC 3.1.11.-)	protein	648	42% helix, 19% strand	Q5SJ47

Pockets

5 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	899	0.70	0.75	110	empty
2	289	0.66	0.82	31	empty
3	182	0.54	0.79	28	empty
4	106	0.36	0.74	21	empty
5	51	0.32	0.77	14	empty

Compared structures

2ZXO · Crystal structure of RecJ from Thermus thermophilus HB8 · the same entry in another collection · chain A against A, TM-score 1.00
Q5SJ47 · AlphaFold monomer V2.0 prediction for single-stranded-DNA-specific exonuclease recj… · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q5SJ47
Elsewhere: RCSB PDB 2ZXO · PDBe 2ZXO · UniProt Q5SJ47

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