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Lyn tyrosine kinase domain, apo form

Analyse Lyn tyrosine kinase domain, apo form in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2ZV7
Type: protein
Length: 257 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Tyrosine-protein kinase lyn
EC: 2.7.10.2
UniProt: P25911
Pockets: 1 · best druggability 0.68

Structure

x-ray diffraction · 1 distinct chain · 40% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Tyrosine-protein kinase lyn (EC 2.7.10.2)	protein	257	40% helix, 18% strand	P25911

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	426	0.68	0.80	48	empty

Compared structures

2ZV7 · Lyn Tyrosine Kinase Domain, apo form · the same entry in another collection · chain A against A, TM-score 1.00
P25911 · AlphaFold monomer V2.0 prediction for tyrosine-protein kinase lyn (P25911) · a predicted model of the same protein · chain A against A, TM-score 0.92

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P25911
Elsewhere: RCSB PDB 2ZV7 · PDBe 2ZV7 · UniProt P25911

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