Research workbench
Mtruva form II
Analyse Mtruva form II in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2ZTC
- Type
- protein
- Length
- 750 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Holliday junction ATP-dependent DNA helicase ruva
- EC
- 3.6.1.-
- UniProt
- P66744
- Pockets
- 6 · best druggability 0.84
Structure
x-ray diffraction · 2 distinct chains · 49% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, D | Holliday junction ATP-dependent DNA helicase ruva (EC 3.6.1.-) | protein | 188 | 49% helix, 22% strand | P66744 |
| B, C | Holliday junction ATP-dependent DNA helicase ruva (EC 3.6.1.-) | protein | 187 | 48% helix, 22% strand | P66744 |
Ligands and binding sites
- GOL · Glycerol · additive · 4 copies · chains A, B, C, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
6 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 223 | 0.84 | 0.95 | 35 | empty |
| 2 | 481 | 0.67 | 0.78 | 52 | empty |
| 3 | 516 | 0.67 | 0.78 | 54 | empty |
| 4 | 488 | 0.66 | 0.78 | 56 | empty |
| 5 | 431 | 0.64 | 0.78 | 51 | GOL |
Interfaces
6 interfaces between chains.
- A–C · 1291 Ų buried · 9 hydrogen bonds · protein-protein
- A–B · 1289 Ų buried · 9 hydrogen bonds · protein-protein
- B–D · 1279 Ų buried · 7 hydrogen bonds · protein-protein
- C–D · 1269 Ų buried · 11 hydrogen bonds · protein-protein
- B–C · 22 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 2ZTC · MtRuvA Form II · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P66744
- Elsewhere: RCSB PDB 2ZTC · PDBe 2ZTC · UniProt P66744
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