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Free aspartyl-tRNA synthetase (asprs) (E.C. 6.1.1.12) from yeast

Analyse Free aspartyl-tRNA synthetase (asprs) (E.C. 6.1.1.12) from yeast in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1EOV
Type: protein
Length: 487 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Aspartyl-tRNA synthetase
EC: 6.1.1.12
UniProt: P04802
Pockets: 7 · best druggability 0.72

Structure

x-ray diffraction · 1 distinct chain · 31% helix, 26% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Aspartyl-tRNA synthetase (EC 6.1.1.12)	protein	487	31% helix, 26% strand	P04802

Pockets

7 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	685	0.72	0.79	68	empty
2	212	0.50	0.76	33	empty
3	76	0.48	0.83	23	empty
4	94	0.45	0.80	18	empty
5	97	0.39	0.76	24	empty

Compared structures

1EOV · Free aspartyl-tRNA synthetase (asprs) (E.C. 6.1.1.12) from yeast · the same entry in another collection · chain A against A, TM-score 1.00
P04802 · AlphaFold monomer V2.0 prediction for aspartate--tRNA ligase, cytoplasmic (P04802) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P04802
Elsewhere: RCSB PDB 1EOV · PDBe 1EOV · UniProt P04802

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