Research workbench
Structure of a C-terminal deletion mutant of thermoplasma acidophilum aldohexose dehydrogenase (aldt)
Analyse Structure of a C-terminal deletion mutant of thermoplasma acidophilum… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2ZK7
- Type
- protein
- Length
- 476 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Glucose 1-dehydrogenase related protein
- EC
- 1.1.1.118
- UniProt
- Q9HK51
- Pockets
- 6 · best druggability 0.66
Structure
x-ray diffraction · 2 distinct chains · 48% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Glucose 1-dehydrogenase related protein (EC 1.1.1.118) | protein | 230 | 47% helix, 16% strand | Q9HK51 |
| B | Glucose 1-dehydrogenase related protein (EC 1.1.1.118) | protein | 246 | 48% helix, 15% strand | Q9HK51 |
Pockets
6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 163 | 0.66 | 0.86 | 30 | empty |
| 2 | 332 | 0.60 | 0.77 | 39 | empty |
| 3 | 263 | 0.49 | 0.73 | 34 | empty |
| 4 | 104 | 0.47 | 0.80 | 19 | empty |
| 5 | 190 | 0.47 | 0.75 | 26 | empty |
Interfaces
1 interface between chains.
- A–B · 1121 Ų buried · 3 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
- 2ZK7 · Structure of a C-terminal deletion mutant of Thermoplasma acidophilum aldohexose… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9HK51
- Elsewhere: RCSB PDB 2ZK7 · PDBe 2ZK7 · UniProt Q9HK51
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