Research workbench
Complex structure of afcca with trnaminida
Analyse Complex structure of afcca with trnaminida in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2ZH1
- Type
- protein + RNA
- Length
- 470 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cca-adding enzyme; RNA (33-mer)
- EC
- 2.7.7.25, 2.7.7.21
- UniProt
- O28126
- Ligands
- SO4
- Pockets
- 5 · best druggability 0.77
Structure
x-ray diffraction · 2 distinct chains · 44% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Cca-adding enzyme (EC 2.7.7.25, 2.7.7.21) | protein | 437 | 44% helix, 21% strand | O28126 |
| B | RNA (33-mer) | rna | 33 | — | — |
Ligands and binding sites
- SO4 · Sulfate ion · ion · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
5 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 758 | 0.77 | 0.81 | 58 | SO4 |
| 2 | 645 | 0.62 | 0.73 | 49 | empty |
| 3 | 505 | 0.57 | 0.73 | 31 | SO4 |
| 4 | 359 | 0.54 | 0.74 | 27 | empty |
| 5 | 57 | 0.32 | 0.76 | 13 | empty |
Interfaces
1 interface between chains.
- A–B · 1259 Ų buried · 29 hydrogen bonds · protein-nucleic
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O28126
- Elsewhere: RCSB PDB 2ZH1 · PDBe 2ZH1 · UniProt O28126
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.