Research workbench
Crystal structure of the KIF1A motor domain after mg release
Analyse Crystal structure of the KIF1A motor domain after mg release in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2ZFM
- Type
- protein
- Length
- 328 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Kinesin-like protein KIF1A, kinesin heavy chain isoform 5C
- UniProt
- P33173, P28738
- Ligands
- ADP
- Pockets
- 2 · best druggability 0.57
Structure
x-ray diffraction · 1 distinct chain · 31% helix, 31% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Kinesin-like protein KIF1A, kinesin heavy chain isoform 5C | protein | 328 | 31% helix, 31% strand | P33173, P28738 |
Ligands and binding sites
- ADP · Adenosine-5'-diphosphate · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 243 | 0.57 | 0.78 | 33 | empty |
| 2 | 299 | 0.56 | 0.77 | 44 | ADP |
Compared structures
- 2ZFM · Crystal Structure of the Kif1A Motor Domain After Mg Release · the same entry in another collection · chain A against A, TM-score 1.00
- P33173 · AlphaFold monomer V2.0 prediction for kinesin-like protein KIF1A (P33173) · a predicted model of the same protein · chain A against A, TM-score 0.97
- P28738 · AlphaFold monomer V2.0 prediction for kinesin heavy chain isoform 5C (P28738) · a predicted model of the same protein · chain A against A, TM-score 0.89
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P33173
- Every structure of UniProt P28738
- Elsewhere: RCSB PDB 2ZFM · PDBe 2ZFM · UniProt P33173 · UniProt P28738
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