Research workbench
The structure of VPS75 (vacuolar protein sorting-associated protein 75)
Analyse The structure of VPS75 (vacuolar protein sorting-associated protein 75) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2ZD7
- Type
- protein
- Length
- 447 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Vacuolar protein sorting-associated protein 75; Evdlplsdeepss
- UniProt
- P53853
- Pockets
- 3 · best druggability 0.50
Structure
x-ray diffraction · 3 distinct chains · 50% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Vacuolar protein sorting-associated protein 75 | protein | 222 | 51% helix, 14% strand | P53853 |
| B | Vacuolar protein sorting-associated protein 75 | protein | 212 | 51% helix, 15% strand | P53853 |
| C | Evdlplsdeepss | protein | 13 | 0% helix, 0% strand | — |
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 128 | 0.50 | 0.80 | 28 | empty |
| 2 | 154 | 0.44 | 0.75 | 28 | empty |
| 3 | 59 | 0.42 | 0.82 | 16 | empty |
Interfaces
1 interface between chains.
- A–B · 1573 Ų buried · 5 hydrogen bonds · protein-protein
Compared structures
- 2ZD7 · The structure of VPS75 (Vacuolar protein sorting-associated protein 75) · the same entry in another collection · chain A against A, TM-score 1.00
- P53853 · AlphaFold monomer V2.0 prediction for vacuolar protein sorting- associated protein 75… · a predicted model of the same protein · chain B against A, TM-score 0.93
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P53853
- Elsewhere: RCSB PDB 2ZD7 · PDBe 2ZD7 · UniProt P53853
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