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Crystal structure of family 7 alginate lyase A1-II' H191N/Y284F in complex with substrate (ggmg)

Analyse Crystal structure of family 7 alginate lyase A1-II' H191N/Y284F in complex with… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2ZAA
Type: protein
Length: 232 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Alginate lyase
EC: 4.2.2.3
UniProt: Q75WP3
Ligands: LGU, MAW, BEM
Pockets: 1 · best druggability 0.49

Structure

x-ray diffraction · 1 distinct chain · 7% helix, 50% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Alginate lyase (EC 4.2.2.3)	protein	232	7% helix, 50% strand	Q75WP3

Ligands and binding sites

LGU · alpha-L-gulopyranuronic acid · ligand · 2 copies · chains A
MAW · 4-deoxy-alpha-L-erythro-hex-4-enopyranuronic acid · ligand · chains A
BEM · beta-D-mannopyranuronic acid · sugar · chains A
GOL · Glycerol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	190	0.49	0.76	30	LGU, BEM, MAW

Compared structures

2ZAA · Crystal Structure of Family 7 Alginate Lyase A1-II' H191N/Y284F in Complex with Substrate… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

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Every structure of UniProt Q75WP3
Elsewhere: RCSB PDB 2ZAA · PDBe 2ZAA · UniProt Q75WP3

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