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Crystal structure of the sensor domain of the transcriptional regulator dnr from pseudomonas aeruginosa

Analyse Crystal structure of the sensor domain of the transcriptional regulator dnr… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2Z69
Type: protein
Length: 436 residues
Chains: 3
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Dnr protein
UniProt: Q51441
Pockets: 4 · best druggability 0.59

Structure

x-ray diffraction · 3 distinct chains · 28% helix, 30% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Dnr protein	protein	148	32% helix, 26% strand	Q51441
B	Dnr protein	protein	150	30% helix, 30% strand	Q51441
C	Dnr protein	protein	138	23% helix, 34% strand	Q51441

Pockets

4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	186	0.59	0.81	38	empty
2	281	0.57	0.77	29	empty
3	88	0.32	0.73	18	empty
4	50	0.27	0.74	12	empty

Interfaces

2 interfaces between chains.

A–B · 1877 Å² buried · 24 hydrogen bonds · protein-protein
B–C · 475 Å² buried · 0 hydrogen bonds · protein-protein

Compared structures

2Z69 · Crystal Structure of the sensor domain of the transcriptional regulator DNR from… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q51441
Elsewhere: RCSB PDB 2Z69 · PDBe 2Z69 · UniProt Q51441

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