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Crystal structure of MJ0684 from methanococcus jannaschii reveals its similarity in the active site to kynurenine aminotransferases

Analyse Crystal structure of MJ0684 from methanococcus jannaschii reveals its… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2Z61
Type: protein
Length: 369 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Probable aspartate aminotransferase 2
EC: 2.6.1.1
UniProt: Q58097
Pockets: 3 · best druggability 0.57

Structure

x-ray diffraction · 1 distinct chain · 47% helix, 14% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Probable aspartate aminotransferase 2 (EC 2.6.1.1)	protein	369	47% helix, 14% strand	Q58097

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	151	0.57	0.82	22	empty
2	194	0.49	0.76	25	empty
3	90	0.38	0.76	25	empty

Modifications

Observed in the structure: 1 modified (cofactor).

Compared structures

2Z61 · Crystal structure of MJ0684 from Methanococcus jannaschii reveals its similarity in the… · the same entry in another collection · chain A against A, TM-score 1.00
Q58097 · AlphaFold monomer V2.0 prediction for (5-formylfuran-3-YL)METHYL phosphate transaminase… · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q58097
Elsewhere: RCSB PDB 2Z61 · PDBe 2Z61 · UniProt Q58097

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