Research workbench

Crystal structure of human leukemia inhibitory factor (lif)

Analyse Crystal structure of human leukemia inhibitory factor (lif) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1EMR
Type: protein
Length: 159 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Leukemia inhibitory factor
UniProt: P15018
Pockets: 1 · best druggability 0.54

Structure

x-ray diffraction · 1 distinct chain · 68% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Leukemia inhibitory factor	protein	159	68% helix, 0% strand	P15018

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	99	0.54	0.84	17	empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

1EMR · Crystal structure of human leukemia inhibitory factor (lif) · the same entry in another collection · chain A against A, TM-score 1.00
P15018 · AlphaFold monomer V2.0 prediction for leukemia inhibitory factor (P15018) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P15018
Elsewhere: RCSB PDB 1EMR · PDBe 1EMR · UniProt P15018

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.