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Crystal structure of phosphoribosylaminoimidazole synthetase from geobacillus kaustophilus

Analyse Crystal structure of phosphoribosylaminoimidazole synthetase from geobacillus… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2Z01
Type: protein
Length: 313 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Phosphoribosylformylglycinamidine cyclo-ligase
EC: 6.3.3.1
UniProt: Q5L3D0
Pockets: 3 · best druggability 0.50

Structure

x-ray diffraction · 1 distinct chain · 40% helix, 25% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1)	protein	313	40% helix, 25% strand	Q5L3D0

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	141	0.50	0.80	20	empty
2	85	0.36	0.76	14	empty
3	57	0.30	0.75	14	empty

Compared structures

2Z01 · Crystal structure of phosphoribosylaminoimidazole synthetase from Geobacillus kaustophilus · the same entry in another collection · chain A against A, TM-score 1.00
Q5L3D0 · AlphaFold monomer V2.0 prediction for phosphoribosylformylglycinamidine cyclo-ligase… · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q5L3D0
Elsewhere: RCSB PDB 2Z01 · PDBe 2Z01 · UniProt Q5L3D0

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