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Crystal structure of btb domain from mouse HKR3

Analyse Crystal structure of btb domain from mouse HKR3 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2YY9
Type: protein
Length: 215 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Zinc finger and btb domain-containing protein 48
UniProt: Q1H9T6
Pockets: 1 · best druggability 0.29

Structure

x-ray diffraction · 2 distinct chains · 57% helix, 12% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Zinc finger and btb domain-containing protein 48	protein	106	58% helix, 12% strand	Q1H9T6
B	Zinc finger and btb domain-containing protein 48	protein	109	56% helix, 12% strand	Q1H9T6

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	51	0.29	0.75	17	empty

Interfaces

1 interface between chains.

A–B · 1030 Å² buried · 8 hydrogen bonds · protein-protein

Compared structures

2YY9 · Crystal structure of BTB domain from mouse HKR3 · the same entry in another collection · chain A against A, TM-score 1.00
Q1H9T6 · AlphaFold monomer V2.0 prediction for telomere zinc finger-associated protein (Q1H9T6) · a predicted model of the same protein · chain A against A, TM-score 0.81

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q1H9T6
Elsewhere: RCSB PDB 2YY9 · PDBe 2YY9 · UniProt Q1H9T6

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