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Crystal structure of translation elongation factor ef-1 beta from pyrococcus horikoshii
Analyse Crystal structure of translation elongation factor ef-1 beta from pyrococcus… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2YY3
- Type
- protein
- Length
- 273 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Elongation factor 1-beta
- UniProt
- P58748
- Pockets
- 3 · best druggability 0.47
Structure
x-ray diffraction · 1 distinct chain · 23% helix, 42% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C | Elongation factor 1-beta | protein | 91 | 23% helix, 42% strand | P58748 |
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 166 | 0.47 | 0.76 | 32 | empty |
| 2 | 104 | 0.45 | 0.79 | 18 | empty |
| 3 | 50 | 0.33 | 0.78 | 14 | empty |
Interfaces
2 interfaces between chains.
- A–B · 540 Ų buried · 9 hydrogen bonds · protein-protein
- A–C · 197 Ų buried · 1 hydrogen bond · protein-protein
Modifications
Observed in the structure: 6 modified (engineered).
Compared structures
- 2YY3 · Crystal Structure of translation elongation factor EF-1 beta from Pyrococcus horikoshii · the same entry in another collection · chain A against A, TM-score 1.00
- P58748 · AlphaFold monomer V2.0 prediction for elongation factor 1-beta (P58748) · a predicted model of the same protein · chain C against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P58748
- Elsewhere: RCSB PDB 2YY3 · PDBe 2YY3 · UniProt P58748
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