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Crystal structure of escherichia COLI diaa

Analyse Crystal structure of escherichia COLI diaa in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2YVA
Type: protein
Length: 386 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Dnaa initiator-associating protein diaa
UniProt: P66817
Pockets: 2 · best druggability 0.54

Structure

x-ray diffraction · 1 distinct chain · 56% helix, 12% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Dnaa initiator-associating protein diaa	protein	193	56% helix, 12% strand	P66817

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	287	0.54	0.75	43	empty
2	243	0.50	0.75	39	empty

Interfaces

1 interface between chains.

A–B · 1883 Å² buried · 23 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

2YVA · Crystal structure of Escherichia coli DiaA · the same entry in another collection · chain A against A, TM-score 1.00
P66817 · AlphaFold monomer V2.0 prediction for dnaa initiator-associating protein diaa (P66817) · a predicted model of the same protein · chain B against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P66817
Elsewhere: RCSB PDB 2YVA · PDBe 2YVA · UniProt P66817

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