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Solution structure of the NCD2 domain in human transcriptional repressor NAB1 protein

Analyse Solution structure of the NCD2 domain in human transcriptional repressor NAB1… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
2YUF
Type
protein
Length
142 residues
Chains
1
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Ngfi-a-binding protein 1
UniProt
Q13506
Pockets
4 · best druggability 0.40

Structure

solution nmr · 1 distinct chain · 58% helix, 0% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ANgfi-a-binding protein 1protein14258% helix, 0% strandQ13506

Pockets

4 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11570.400.7323empty
2510.340.7813empty
3500.320.7718empty
4590.290.7412empty

Compared structures

  • 2YUF · Solution structure of the NCD2 domain in human transcriptional repressor Nab1 protein · the same entry in another collection · chain A against A, TM-score 1.00
  • Q13506 · AlphaFold monomer V2.0 prediction for ngfi-a-binding protein 1 (Q13506) · a predicted model of the same protein · chain A against A, TM-score 0.82

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