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Solution structure of the PDZ domain from mouse lim domain kinase

Analyse Solution structure of the PDZ domain from mouse lim domain kinase in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2YUB
Type: protein
Length: 118 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Lim domain kinase 2
EC: 2.7.11.1
UniProt: O54785
Pockets: 1 · best druggability 0.27

Structure

solution nmr · 1 distinct chain · 11% helix, 25% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Lim domain kinase 2 (EC 2.7.11.1)	protein	118	11% helix, 25% strand	O54785

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	58	0.27	0.73	15	empty

Compared structures

2YUB · Solution structure of the PDZ domain from mouse LIM domain kinase · the same entry in another collection · chain A against A, TM-score 1.00
O54785 · AlphaFold monomer V2.0 prediction for lim domain kinase 2 (O54785) · a predicted model of the same protein · chain A against A, TM-score 0.73

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O54785
Elsewhere: RCSB PDB 2YUB · PDBe 2YUB · UniProt O54785

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