Research workbench
Crystal structure of hypothetical methyltransferase TTHA0223 from thermus thermophilus HB8
Analyse Crystal structure of hypothetical methyltransferase TTHA0223 from thermus… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2YR0
- Type
- protein
- Length
- 492 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Hypothetical protein TTHA0223
- EC
- 2.1.1.-
- UniProt
- Q5SLS0
- Pockets
- 2 · best druggability 0.74
Structure
x-ray diffraction · 1 distinct chain · 43% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Hypothetical protein TTHA0223 (EC 2.1.1.-) | protein | 246 | 43% helix, 25% strand | Q5SLS0 |
Pockets
2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 947 | 0.74 | 0.77 | 66 | empty |
| 2 | 1097 | 0.73 | 0.76 | 87 | empty |
Interfaces
1 interface between chains.
- A–B · 802 Ų buried · 11 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 6 modified (engineered).
Compared structures
- 2YR0 · Crystal Structure of Hypothetical Methyltransferase TTHA0223 from Thermus thermophilus HB8 · the same entry in another collection · chain B against B, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5SLS0
- Elsewhere: RCSB PDB 2YR0 · PDBe 2YR0 · UniProt Q5SLS0
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