Research workbench
Mhv-68 lana (ORF73) C-terminal domain: triclinic crystal form
Analyse Mhv-68 lana (ORF73) C-terminal domain: triclinic crystal form in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2YQ1
- Type
- protein
- Length
- 516 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- ORF73
- UniProt
- O41974
- Pockets
- 7 · best druggability 0.54
Structure
x-ray diffraction · 4 distinct chains · 33% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | ORF73 | protein | 130 | 30% helix, 20% strand | O41974 |
| B | ORF73 | protein | 127 | 35% helix, 20% strand | O41974 |
| C | ORF73 | protein | 131 | 30% helix, 20% strand | O41974 |
| D | ORF73 | protein | 128 | 35% helix, 20% strand | O41974 |
Pockets
7 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 198 | 0.54 | 0.79 | 36 | empty |
| 2 | 110 | 0.44 | 0.78 | 19 | empty |
| 3 | 92 | 0.38 | 0.76 | 20 | empty |
| 4 | 69 | 0.37 | 0.78 | 16 | empty |
| 5 | 69 | 0.31 | 0.74 | 17 | empty |
Interfaces
6 interfaces between chains.
- C–D · 1776 Ų buried · 8 hydrogen bonds · protein-protein
- A–B · 1665 Ų buried · 9 hydrogen bonds · protein-protein
- A–C · 648 Ų buried · 11 hydrogen bonds · protein-protein
- B–C · 256 Ų buried · 2 hydrogen bonds · protein-protein
- A–D · 244 Ų buried · 3 hydrogen bonds · protein-protein
Compared structures
- 2YQ1 · MHV-68 LANA (ORF73) C-terminal domain: triclinic crystal form · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O41974
- Elsewhere: RCSB PDB 2YQ1 · PDBe 2YQ1 · UniProt O41974
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