Research workbench
Salmonella enterica sada 1185-1386 fused to GCN4 adaptors (SADAK14)
Analyse Salmonella enterica sada 1185-1386 fused to GCN4 adaptors (SADAK14) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2YO3
- Type
- protein
- Length
- 772 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- General control protein GCN4, putative inner membrane protein, general control protein…
- UniProt
- P03069, Q8ZL64
- Ligands
- CL
- Pockets
- 1 · best druggability 0.27
Structure
x-ray diffraction · 3 distinct chains · 52% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | General control protein GCN4, putative inner membrane protein, general control protein GCN4 | protein | 257 | 52% helix, 16% strand | P03069, Q8ZL64 |
| B | General control protein GCN4, putative inner membrane protein, general control protein GCN4 | protein | 258 | 52% helix, 16% strand | P03069, Q8ZL64 |
| C | General control protein GCN4, putative inner membrane protein, general control protein GCN4 | protein | 257 | 52% helix, 16% strand | P03069, Q8ZL64 |
Ligands and binding sites
- CL · Chloride ion · ion · chains A, B, C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 52 | 0.27 | 0.75 | 19 | empty |
Interfaces
3 interfaces between chains.
- A–C · 5698 Ų buried · 86 hydrogen bonds · protein-protein
- A–B · 5661 Ų buried · 89 hydrogen bonds · protein-protein
- B–C · 5530 Ų buried · 90 hydrogen bonds · protein-protein
Compared structures
- 2YO3 · Salmonella enterica SadA 1185-1386 fused to GCN4 adaptors (SadAK14) · the same entry in another collection · chain A against A, TM-score 1.00
- Q8ZL64 · AlphaFold monomer V2.0 prediction for autotransporter adhesin sada (Q8ZL64) · a predicted model of the same protein · chain C against A, TM-score 0.62
- P03069 · AlphaFold monomer V2.0 prediction for general control transcription factor GCN4 (P03069) · a predicted model of the same protein · chain A against A, TM-score 0.21
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P03069
- Every structure of UniProt Q8ZL64
- Elsewhere: RCSB PDB 2YO3 · PDBe 2YO3 · UniProt P03069 · UniProt Q8ZL64
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