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MIMP_ALPHADIBB_B54NLS

Analyse MIMP_ALPHADIBB_B54NLS in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2YNR
Type: protein
Length: 437 residues
Chains: 3
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Importin subunit alpha; B54NLS
UniProt: Q52L97
Pockets: 1 · best druggability 0.44

Structure

x-ray diffraction · 3 distinct chains · 71% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Importin subunit alpha	protein	425	73% helix, 0% strand	Q52L97
B	B54NLS	protein	7	0% helix, 0% strand	—
C	B54NLS	protein	5	0% helix, 0% strand	—

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	67	0.44	0.81	13	empty

Interfaces

2 interfaces between chains.

A–B · 714 Å² buried · 15 hydrogen bonds · protein-protein
A–C · 557 Å² buried · 17 hydrogen bonds · protein-protein

Compared structures

2YNR · mImp_alphadIBB_B54NLS · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q52L97
Elsewhere: RCSB PDB 2YNR · PDBe 2YNR · UniProt Q52L97

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