Research workbench

Human myotubularin related protein 6 (MTMR6)

Analyse Human myotubularin related protein 6 (MTMR6) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2YF0
Type: protein
Length: 487 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Myotubularin-related protein 6
EC: 3.1.3.-
UniProt: Q9Y217
Ligands: SO4
Pockets: 5 · best druggability 0.60

Structure

x-ray diffraction · 1 distinct chain · 40% helix, 16% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Myotubularin-related protein 6 (EC 3.1.3.-)	protein	487	40% helix, 16% strand	Q9Y217

Ligands and binding sites

SO4 · Sulfate ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	292	0.60	0.79	29	empty
2	59	0.52	0.86	20	empty
3	75	0.37	0.77	18	empty
4	56	0.31	0.76	18	SO4
5	55	0.25	0.73	14	empty

Compared structures

2YF0 · Human Myotubularin related protein 6 (MTMR6) · the same entry in another collection · chain A against A, TM-score 1.00
Q9Y217 · AlphaFold monomer V2.0 prediction for myotubularin-related protein 6 (Q9Y217) · a predicted model of the same protein · chain A against A, TM-score 0.80

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9Y217
Elsewhere: RCSB PDB 2YF0 · PDBe 2YF0 · UniProt Q9Y217

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.