Complex of RAD18 (RAD6 binding domain) with RAD6B

Structure

x-ray diffraction · 2 distinct chains · 40% helix, 18% strand (DSSP).

Ligands and binding sites

• NA · Sodium ion · metal · chains A
• SO4 · Sulfate ion · ion · 2 copies · chains A, B
• BME · Beta-mercaptoethanol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

• A–B · 914 Ų buried · 15 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 1 covalent (additive adduct).

Compared structures

• 2YBF · Complex of Rad18 (Rad6 binding domain) with Rad6b · the same entry in another collection · chain A against A, TM-score 1.00
• P63146 · AlphaFold monomer V2.0 prediction for ubiquitin-conjugating enzyme E2 B (P63146) · a predicted model of the same protein · chain A against A, TM-score 0.99
• Q9NS91 · AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase RAD18 (Q9NS91) · a predicted model of the same protein · chain B against A, TM-score 0.53

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P63146
• Every structure of UniProt Q9NS91
• Elsewhere: RCSB PDB 2YBF · PDBe 2YBF · UniProt P63146 · UniProt Q9NS91