Research workbench
Crystal structure of an outer membrane-anchored endolytic peptidoglycan lytic transglycosylase (mlte) from escherichia COLI
Analyse Crystal structure of an outer membrane-anchored endolytic peptidoglycan lytic… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2Y8P
- Type
- protein
- Length
- 378 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Endo-type membrane-bound lytic murein transglycosylase a
- EC
- 4.2.2.-
- UniProt
- P0C960
- Pockets
- 3 · best druggability 0.68
Structure
x-ray diffraction · 2 distinct chains · 63% helix, 2% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Endo-type membrane-bound lytic murein transglycosylase a (EC 4.2.2.-) | protein | 190 | 63% helix, 2% strand | P0C960 |
| B | Endo-type membrane-bound lytic murein transglycosylase a (EC 4.2.2.-) | protein | 188 | 64% helix, 2% strand | P0C960 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 202 | 0.68 | 0.86 | 31 | empty |
| 2 | 66 | 0.31 | 0.74 | 14 | empty |
| 3 | 50 | 0.27 | 0.74 | 15 | empty |
Interfaces
1 interface between chains.
- A–B · 579 Ų buried · 10 hydrogen bonds · protein-protein
Compared structures
- 2Y8P · Crystal Structure of an Outer Membrane-Anchored Endolytic Peptidoglycan Lytic… · the same entry in another collection · chain A against A, TM-score 1.00
- P0C960 · AlphaFold monomer V2.0 prediction for endo-type membrane-bound lytic murein… · a predicted model of the same protein · chain B against A, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0C960
- Elsewhere: RCSB PDB 2Y8P · PDBe 2Y8P · UniProt P0C960
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