Research workbench
Crystal structure of mycobacterium tuberculosis phosphoribosyl isomerase a (variant D11N)
Analyse Crystal structure of mycobacterium tuberculosis phosphoribosyl isomerase a… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2Y89
- Type
- protein
- Length
- 240 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Phosphoribosyl isomerase a
- EC
- 5.3.1.24, 5.3.1.16
- UniProt
- P60578
- Ligands
- SO4
- Pockets
- 2 · best druggability 0.64
Structure
x-ray diffraction · 1 distinct chain · 40% helix, 28% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Phosphoribosyl isomerase a (EC 5.3.1.24, 5.3.1.16) | protein | 240 | 40% helix, 28% strand | P60578 |
Ligands and binding sites
- SO4 · Sulfate ion · ion · 7 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 331 | 0.64 | 0.80 | 42 | SO4 |
| 2 | 58 | 0.40 | 0.81 | 20 | empty |
Compared structures
- 2Y89 · Crystal structure of mycobacterium tuberculosis phosphoribosyl isomerase a (variant D11N) · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P60578
- Elsewhere: RCSB PDB 2Y89 · PDBe 2Y89 · UniProt P60578
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.