Research workbench
N-terminal head domain and beginning of coiled coil domain of danio rerio sas-6
Analyse N-terminal head domain and beginning of coiled coil domain of danio rerio sas-6 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2Y3W
- Type
- protein
- Length
- 441 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Spindle assembly abnormal protein 6 homolog
- UniProt
- Q7ZVT3
- Pockets
- 3 · best druggability 0.75
Structure
x-ray diffraction · 3 distinct chains · 31% helix, 43% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Spindle assembly abnormal protein 6 homolog | protein | 172 | 34% helix, 44% strand | Q7ZVT3 |
| B | Spindle assembly abnormal protein 6 homolog | protein | 166 | 34% helix, 39% strand | Q7ZVT3 |
| C | Spindle assembly abnormal protein 6 homolog | protein | 103 | 20% helix, 49% strand | Q7ZVT3 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1166 | 0.75 | 0.77 | 100 | empty |
| 2 | 62 | 0.37 | 0.78 | 12 | empty |
| 3 | 50 | 0.27 | 0.74 | 12 | empty |
Interfaces
3 interfaces between chains.
- A–B · 1186 Ų buried · 7 hydrogen bonds · protein-protein
- A–C · 769 Ų buried · 10 hydrogen bonds · protein-protein
- B–C · 208 Ų buried · 4 hydrogen bonds · protein-protein
Compared structures
- 2Y3W · N-terminal head domain and beginning of coiled coil domain of Danio rerio SAS-6 · the same entry in another collection · chain A against A, TM-score 1.00
- Q7ZVT3 · AlphaFold monomer V2.0 prediction for spindle assembly abnormal protein 6 homolog (Q7ZVT3) · a predicted model of the same protein · chain C against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q7ZVT3
- Elsewhere: RCSB PDB 2Y3W · PDBe 2Y3W · UniProt Q7ZVT3
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.