Research workbench
Crystal structure of the phosphoenolpyruvate-binding domain of enzyme I in complex with phosphoenolpyruvate from the thermoanaerobacter tengcongensis pep-sugar phosphotransferase system (pts)
Analyse Crystal structure of the phosphoenolpyruvate-binding domain of enzyme I in… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2XZ7
- Type
- protein
- Length
- 324 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Phosphoenolpyruvate-protein kinase (pts system ei component in bacteria)
- EC
- 2.7.3.9
- UniProt
- Q8R7R4
- Ligands
- PEP, MG
- Pockets
- 2 · best druggability 0.51
Structure
x-ray diffraction · 1 distinct chain · 52% helix, 12% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Phosphoenolpyruvate-protein kinase (pts system ei component in bacteria) (EC 2.7.3.9) | protein | 324 | 52% helix, 12% strand | Q8R7R4 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 159 | 0.51 | 0.79 | 27 | PEP, MG |
| 2 | 59 | 0.33 | 0.76 | 13 | empty |
Compared structures
- 2XZ7 · Crystal structure of the phosphoenolpyruvate-binding domain of enzyme I in complex with… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8R7R4
- Elsewhere: RCSB PDB 2XZ7 · PDBe 2XZ7 · UniProt Q8R7R4
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