The structure of the 2:1 (partially occupied) complex between stearoyl acyl carrier protein desaturase from ricinus communis (castor bean) and acyl carrier protein.

Structure

x-ray diffraction · 2 distinct chains · 62% helix, 1% strand (DSSP).

Ligands and binding sites

• FE · Fe (III) ion · metal · 6 copies · chains A, B, C
• ZN · Zinc ion · metal · 3 copies · chains A, B, C
• EDO · 1,2-ethanediol · additive · chains B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

14 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.

Interfaces

4 interfaces between chains.

• A–B · 2811 Ų buried · 41 hydrogen bonds · protein-protein
• C–D · 667 Ų buried · 8 hydrogen bonds · protein-protein
• B–D · 570 Ų buried · 14 hydrogen bonds · protein-protein
• B–C · 407 Ų buried · 4 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 1 modified (phosphorylation).

Compared structures

• 2XZ0 · The Structure of the 2:1 (Partially Occupied) Complex Between Stearoyl Acyl Carrier… · the same entry in another collection · chain A against A, TM-score 1.00
• P22337 · AlphaFold monomer V2.0 prediction for stearoyl-[acyl-carrier-protein] 9-desaturase… · a predicted model of the same protein · chain A against A, TM-score 0.99
• P07854 · AlphaFold monomer V2.0 prediction for acyl carrier protein 1, chloroplastic (P07854) · a predicted model of the same protein · chain D against A, TM-score 0.87

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P22337
• Every structure of UniProt P07854
• Elsewhere: RCSB PDB 2XZ0 · PDBe 2XZ0 · UniProt P22337 · UniProt P07854