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Crystal structure of apolaccase from thermus thermophilus HB27

Analyse Crystal structure of apolaccase from thermus thermophilus HB27 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2XUW
Type: protein
Length: 439 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Laccase
EC: 1.10.3.2
UniProt: Q72HW2
Pockets: 4 · best druggability 0.61

Structure

x-ray diffraction · 1 distinct chain · 6% helix, 49% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Laccase (EC 1.10.3.2)	protein	439	6% helix, 49% strand	Q72HW2

Ligands and binding sites

MPD · (4S)-2-methyl-2,4-pentanediol · additive · 9 copies · chains A
MRD · (4R)-2-methylpentane-2,4-diol · additive · 7 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	292	0.61	0.79	27	MPD
2	154	0.47	0.77	34	MRD, MPD
3	74	0.37	0.78	22	empty
4	67	0.32	0.75	18	empty

Compared structures

2XUW · Crystal Structure of Apolaccase from Thermus thermophilus HB27 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q72HW2
Elsewhere: RCSB PDB 2XUW · PDBe 2XUW · UniProt Q72HW2

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