Research workbench
Structure of the major pilus backbone protein from streptococcus agalactiae
Analyse Structure of the major pilus backbone protein from streptococcus agalactiae in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2XTL
- Type
- protein
- Length
- 901 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cell wall surface anchor family protein
- UniProt
- Q3DMP5
- Ligands
- K
- Pockets
- 10 · best druggability 0.61
Structure
x-ray diffraction · 2 distinct chains · 15% helix, 44% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Cell wall surface anchor family protein | protein | 449 | 15% helix, 45% strand | Q3DMP5 |
| B | Cell wall surface anchor family protein | protein | 452 | 15% helix, 44% strand | Q3DMP5 |
Ligands and binding sites
- K · Potassium ion · metal · 3 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
10 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 351 | 0.61 | 0.78 | 44 | empty |
| 2 | 253 | 0.57 | 0.78 | 26 | empty |
| 3 | 231 | 0.54 | 0.78 | 40 | empty |
| 4 | 101 | 0.53 | 0.83 | 21 | empty |
| 5 | 113 | 0.51 | 0.82 | 29 | empty |
Interfaces
1 interface between chains.
- A–B · 603 Ų buried · 9 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 6 isopeptide (isopeptide).
Compared structures
- 2XTL · Structure of the major pilus backbone protein from Streptococcus Agalactiae · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q3DMP5
- Elsewhere: RCSB PDB 2XTL · PDBe 2XTL · UniProt Q3DMP5
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.