Research workbench
Structure and metal-loading of a soluble periplasm cupro-protein: zn- cuca-closed (semet)
Analyse Structure and metal-loading of a soluble periplasm cupro-protein: zn… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2XL9
- Type
- protein
- Length
- 466 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- SLL1785 protein
- UniProt
- P73600
- Ligands
- TAM, ZN
- Pockets
- 2 · best druggability 0.75
Structure
x-ray diffraction · 2 distinct chains · 18% helix, 35% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | SLL1785 protein | protein | 231 | 18% helix, 35% strand | P73600 |
| B | SLL1785 protein | protein | 235 | 19% helix, 34% strand | P73600 |
Ligands and binding sites
- TAM · Tris(hydroxyethyl)aminomethane · ligand · chains A
- ZN · Zinc ion · metal · 3 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 646 | 0.75 | 0.81 | 55 | empty |
| 2 | 69 | 0.41 | 0.80 | 16 | empty |
Interfaces
1 interface between chains.
- A–B · 927 Ų buried · 16 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 16 modified, 2 disulfide (engineered, disulfide).
Compared structures
- 2XL9 · Structure and metal-loading of a soluble periplasm cupro-protein: Zn- CucA-closed (SeMet) · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P73600
- Elsewhere: RCSB PDB 2XL9 · PDBe 2XL9 · UniProt P73600
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