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Dimer structure of the bacterial cell division regulator mipz

Analyse Dimer structure of the bacterial cell division regulator mipz in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2XJ9
Type: protein
Length: 530 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Mipz
UniProt: B8GY04
Ligands: AGS, MG
Pockets: 7 · best druggability 0.84

Structure

x-ray diffraction · 2 distinct chains · 45% helix, 16% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Mipz	protein	265	45% helix, 15% strand	B8GY04
B	Mipz	protein	265	46% helix, 17% strand	B8GY04

Ligands and binding sites

AGS · Phosphothiophosphoric acid-adenylate ester · ligand · 2 copies · chains A, B
MG · Magnesium ion · metal · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

7 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	881	0.84	0.87	86	MG, AGS
2	286	0.60	0.79	45	empty
3	107	0.53	0.83	17	empty
4	90	0.48	0.81	13	empty
5	50	0.36	0.79	14	empty

Interfaces

1 interface between chains.

A–B · 1989 Å² buried · 17 hydrogen bonds · protein-protein

Compared structures

2XJ9 · Dimer Structure of the bacterial cell division regulator MipZ · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt B8GY04
Elsewhere: RCSB PDB 2XJ9 · PDBe 2XJ9 · UniProt B8GY04

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