Research workbench
Crystal structure of pcrh in complex with the chaperone binding region of popd
Analyse Crystal structure of pcrh in complex with the chaperone binding region of popd in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2XCB
- Type
- protein
- Length
- 273 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Regulatory protein pcrh; Pepd
- UniProt
- Q9I325, O50280
- Ligands
- NO3
- Pockets
- 3 · best druggability 0.70
Structure
x-ray diffraction · 3 distinct chains · 76% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Regulatory protein pcrh | protein | 133 | 80% helix, 0% strand | Q9I325 |
| B | Regulatory protein pcrh | protein | 132 | 77% helix, 0% strand | Q9I325 |
| C | Pepd | protein | 8 | 0% helix, 0% strand | O50280 |
Ligands and binding sites
- NO3 · Nitrate ion · ion · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 603 | 0.70 | 0.78 | 46 | empty |
| 2 | 81 | 0.43 | 0.80 | 20 | empty |
| 3 | 52 | 0.29 | 0.74 | 11 | empty |
Interfaces
2 interfaces between chains.
- A–B · 756 Ų buried · 8 hydrogen bonds · protein-protein
- A–C · 534 Ų buried · 7 hydrogen bonds · protein-protein
Compared structures
- 2XCB · Crystal structure of PcrH in complex with the chaperone binding region of PopD · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9I325
- Every structure of UniProt O50280
- Elsewhere: RCSB PDB 2XCB · PDBe 2XCB · UniProt Q9I325 · UniProt O50280
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