Research workbench
Crystal structure of trehalose synthase tret from P. horikoshii (seleno derivative)
Analyse Crystal structure of trehalose synthase tret from P. horikoshii (seleno… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2XA1
- Type
- protein
- Length
- 810 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Trehalose-synthase tret
- UniProt
- O58762
- Pockets
- 4 · best druggability 0.73
Structure
x-ray diffraction · 2 distinct chains · 46% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Trehalose-synthase tret | protein | 404 | 46% helix, 15% strand | O58762 |
| B | Trehalose-synthase tret | protein | 406 | 46% helix, 15% strand | O58762 |
Pockets
4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1056 | 0.73 | 0.76 | 73 | empty |
| 2 | 946 | 0.73 | 0.77 | 69 | empty |
| 3 | 1131 | 0.72 | 0.75 | 77 | empty |
| 4 | 63 | 0.29 | 0.73 | 16 | empty |
Interfaces
1 interface between chains.
- A–B · 317 Ų buried · 6 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 16 modified (engineered).
Compared structures
- 2XA1 · Crystal structure of trehalose synthase TreT from P.horikoshii (Seleno derivative) · the same entry in another collection · chain A against A, TM-score 1.00
- O58762 · AlphaFold monomer V2.0 prediction for trehalose synthase (O58762) · a predicted model of the same protein · chain B against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O58762
- Elsewhere: RCSB PDB 2XA1 · PDBe 2XA1 · UniProt O58762
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