Research workbench
The ternary complex of prnb (the second enzyme in pyrrolnitrin biosynthesis pathway), tryptophan and cyanide
Analyse The ternary complex of prnb (the second enzyme in pyrrolnitrin biosynthesis… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2X67
- Type
- protein
- Length
- 350 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Prnb
- UniProt
- P95481
- Ligands
- HEM, TRP, SO4, CYN
- Pockets
- 2 · best druggability 0.87
Structure
x-ray diffraction · 1 distinct chain · 68% helix, 2% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Prnb | protein | 350 | 68% helix, 2% strand | P95481 |
Ligands and binding sites
- HEM · Protoporphyrin IX containing Fe · ligand · chains A
- TRP · Tryptophan · ligand · chains A
- SO4 · Sulfate ion · ion · 2 copies · chains A
- CYN · Cyanide ion · ion · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 450 | 0.87 | 0.94 | 52 | HEM, TRP, CYN |
| 2 | 55 | 0.28 | 0.74 | 17 | empty |
Compared structures
- 2X67 · The ternary complex of PrnB (the second enzyme in pyrrolnitrin biosynthesis pathway)… · the same entry in another collection · chain A against A, TM-score 1.00
- P95481 · AlphaFold monomer V2.0 prediction for monodechloroaminopyrrolnitrin synthase prnb (P95481) · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P95481
- Elsewhere: RCSB PDB 2X67 · PDBe 2X67 · UniProt P95481
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.