Research workbench
Crystal structure of the ORF131 L26M L51M double mutant from sulfolobus islandicus rudivirus 1
Analyse Crystal structure of the ORF131 L26M L51M double mutant from sulfolobus… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2X5H
- Type
- protein
- Length
- 371 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Orf 131
- UniProt
- Q8QL44
- Ligands
- SO4
- Pockets
- 3 · best druggability 0.71
Structure
x-ray diffraction · 3 distinct chains · 42% helix, 33% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Orf 131 | protein | 92 | 45% helix, 35% strand | Q8QL44 |
| C | Orf 131 | protein | 93 | 41% helix, 31% strand | Q8QL44 |
| D | Orf 131 | protein | 94 | 41% helix, 34% strand | Q8QL44 |
Ligands and binding sites
- SO4 · Sulfate ion · ion · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1099 | 0.71 | 0.75 | 102 | empty |
| 2 | 62 | 0.33 | 0.76 | 15 | empty |
| 3 | 66 | 0.32 | 0.74 | 14 | empty |
Interfaces
5 interfaces between chains.
- B–C · 2505 Ų buried · 24 hydrogen bonds · protein-protein
- A–D · 2474 Ų buried · 30 hydrogen bonds · protein-protein
- A–B · 370 Ų buried · 8 hydrogen bonds · protein-protein
- C–D · 106 Ų buried · 0 hydrogen bonds · protein-protein
- A–C · 59 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 2X5H · Crystal structure of the ORF131 L26M L51M double mutant from Sulfolobus islandicus… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8QL44
- Elsewhere: RCSB PDB 2X5H · PDBe 2X5H · UniProt Q8QL44
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.