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Structure of the CUL5 N-terminal domain at 2.05A resolution.

Analyse Structure of the CUL5 N-terminal domain at 2.05A resolution. in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2WZK
Type: protein
Length: 369 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Cullin-5
UniProt: Q9D5V5
Pockets: 1 · best druggability 0.39

Structure

x-ray diffraction · 1 distinct chain · 78% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Cullin-5	protein	369	78% helix, 0% strand	Q9D5V5

Ligands and binding sites

EDO · 1,2-ethanediol · additive · 5 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	113	0.39	0.75	17	empty

Compared structures

2WZK · Structure of the Cul5 N-terminal domain at 2.05A resolution. · the same entry in another collection · chain A against A, TM-score 1.00
Q9D5V5 · AlphaFold monomer V2.0 prediction for cullin-5 (Q9D5V5) · a predicted model of the same protein · chain A against A, TM-score 0.92

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9D5V5
Elsewhere: RCSB PDB 2WZK · PDBe 2WZK · UniProt Q9D5V5

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