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Neutron structure of a class a beta-lactamase toho-1 E166A R274N R276N triple mutant

Analyse Neutron structure of a class a beta-lactamase toho-1 E166A R274N R276N triple… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2WYX
Type: protein
Length: 256 residues
Chains: 1
Method: neutron diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Beta-lactamse toho-1
EC: 3.5.2.6
UniProt: Q47066
Pockets: 1 · best druggability 0.30

Structure

neutron diffraction · 1 distinct chain · 42% helix, 20% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Beta-lactamse toho-1 (EC 3.5.2.6)	protein	256	42% helix, 20% strand	Q47066

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	69	0.30	0.74	19	empty

Compared structures

2WYX · Neutron structure of a class A Beta-lactamase Toho-1 E166A R274N R276N triple mutant · the same entry in another collection · chain A against A, TM-score 1.00
Q47066 · AlphaFold monomer V2.0 prediction for beta-lactamase toho-1 (Q47066) · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q47066
Elsewhere: RCSB PDB 2WYX · PDBe 2WYX · UniProt Q47066

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