Research workbench
Crystal structure of rat angiotensinogen in C2 space group
Analyse Crystal structure of rat angiotensinogen in C2 space group in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2WXZ
- Type
- protein
- Length
- 835 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Angiotensinogen
- UniProt
- P01015
- Pockets
- 5 · best druggability 0.79
Structure
x-ray diffraction · 2 distinct chains · 30% helix, 32% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Angiotensinogen | protein | 422 | 30% helix, 31% strand | P01015 |
| C | Angiotensinogen | protein | 413 | 31% helix, 32% strand | P01015 |
Pockets
5 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 856 | 0.79 | 0.82 | 70 | empty |
| 2 | 316 | 0.60 | 0.78 | 49 | empty |
| 3 | 289 | 0.60 | 0.78 | 36 | empty |
| 4 | 171 | 0.55 | 0.80 | 19 | empty |
| 5 | 65 | 0.40 | 0.80 | 12 | empty |
Interfaces
1 interface between chains.
- A–C · 641 Ų buried · 5 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P01015
- Elsewhere: RCSB PDB 2WXZ · PDBe 2WXZ · UniProt P01015
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