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Physalis mottle virus: natural empty capsid

Analyse Physalis mottle virus: natural empty capsid in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2WWS
Type: protein
Length: 531 residues
Chains: 3
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Coat protein
UniProt: P36351
Pockets: 6 · best druggability 0.52

Structure

x-ray diffraction · 2 distinct chains · 11% helix, 43% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Coat protein	protein	161	12% helix, 45% strand	P36351
B, C	Coat protein	protein	185	10% helix, 41% strand	P36351

Pockets

6 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	236	0.52	0.76	31	empty
2	61	0.44	0.83	17	empty
3	56	0.37	0.80	17	empty
4	70	0.36	0.77	17	empty
5	59	0.32	0.77	15	empty

Interfaces

3 interfaces between chains.

B–C · 1007 Å² buried · 24 hydrogen bonds · protein-protein
A–C · 736 Å² buried · 16 hydrogen bonds · protein-protein
A–B · 609 Å² buried · 13 hydrogen bonds · protein-protein

Compared structures

2WWS · Physalis Mottle Virus: Natural Empty Capsid · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P36351
Elsewhere: RCSB PDB 2WWS · PDBe 2WWS · UniProt P36351

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