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Structure of the het-S N-terminal domain

Analyse Structure of the het-S N-terminal domain in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2WVO
Type: protein
Length: 444 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Small S protein
UniProt: Q1K9D3
Ligands: CL
Pockets: 7 · best druggability 0.63

Structure

x-ray diffraction · 1 distinct chain · 71% helix, 4% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Small S protein	protein	222	71% helix, 4% strand	Q1K9D3

Ligands and binding sites

CL · Chloride ion · ion · 4 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

7 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	221	0.63	0.82	35	empty
2	103	0.47	0.80	16	empty
3	123	0.47	0.78	17	empty
4	58	0.42	0.82	17	empty
5	128	0.42	0.75	24	CL

Interfaces

1 interface between chains.

A–B · 1001 Å² buried · 16 hydrogen bonds · protein-protein

Compared structures

2WVO · Structure of the HET-S N-terminal domain · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q1K9D3
Elsewhere: RCSB PDB 2WVO · PDBe 2WVO · UniProt Q1K9D3

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