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The crystal structure of srfj from salmonella typhimurium

Analyse The crystal structure of srfj from salmonella typhimurium in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2WNW
Type: protein
Length: 890 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Activated by transcription factor ssrb
UniProt: Q9KIJ7
Ligands: PO4
Pockets: 6 · best druggability 0.85

Structure

x-ray diffraction · 1 distinct chain · 31% helix, 30% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Activated by transcription factor ssrb	protein	445	31% helix, 30% strand	Q9KIJ7

Ligands and binding sites

PO4 · Phosphate ion · ion · 4 copies · chains A, B
GOL · Glycerol · additive · 4 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	774	0.85	0.88	83	GOL
2	431	0.60	0.75	53	GOL
3	341	0.58	0.76	38	GOL
4	144	0.41	0.74	22	empty
5	128	0.39	0.74	24	empty

Interfaces

1 interface between chains.

A–B · 1417 Å² buried · 30 hydrogen bonds · protein-protein

Compared structures

2WNW · The crystal structure of SrfJ from salmonella typhimurium · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9KIJ7
Elsewhere: RCSB PDB 2WNW · PDBe 2WNW · UniProt Q9KIJ7

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