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Crystal structure of human magnesium-dependent phosphatase 1 of the haloacid dehalogenase superfamily (MGC5987)

Analyse Crystal structure of human magnesium-dependent phosphatase 1 of the haloacid… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2WM8
Type: protein
Length: 170 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Magnesium-dependent phosphatase 1
EC: 3.8.1.-
UniProt: Q86V88
Pockets: 1 · best druggability 0.34

Structure

x-ray diffraction · 1 distinct chain · 39% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Magnesium-dependent phosphatase 1 (EC 3.8.1.-)	protein	170	39% helix, 19% strand	Q86V88

Ligands and binding sites

EDO · 1,2-ethanediol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	58	0.34	0.78	14	empty

Compared structures

2WM8 · Crystal structure of human magnesium-dependent phosphatase 1 of the haloacid dehalogenase… · the same entry in another collection · chain A against A, TM-score 1.00
Q86V88 · AlphaFold monomer V2.0 prediction for magnesium-dependent phosphatase 1 (Q86V88) · a predicted model of the same protein · chain A against A, TM-score 0.93

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q86V88
Elsewhere: RCSB PDB 2WM8 · PDBe 2WM8 · UniProt Q86V88

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