Research workbench
Crystal structure of nmra-like family domain containing protein 1 in complex with niflumic acid
Analyse Crystal structure of nmra-like family domain containing protein 1 in complex… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2WM3
- Type
- protein
- Length
- 296 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Nmra-like family domain containing protein 1
- UniProt
- Q9HBL8
- Ligands
- NFL, NAP, PO4, CL
- Pockets
- 1 · best druggability 0.73
Structure
x-ray diffraction · 1 distinct chain · 47% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Nmra-like family domain containing protein 1 | protein | 296 | 47% helix, 16% strand | Q9HBL8 |
Ligands and binding sites
- NFL · 2-{[3-(trifluoromethyl)phenyl]amino}nicotinic acid · ligand · 2 copies · chains A
- NAP · Nadp nicotinamide-adenine-dinucleotide phosphate · ligand · chains A
- PO4 · Phosphate ion · ion · chains A
- CL · Chloride ion · ion · chains A
- GOL · Glycerol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 458 | 0.73 | 0.82 | 48 | NAP, NFL |
Compared structures
- 2WM3 · Crystal structure of NmrA-like family domain containing protein 1 in complex with… · the same entry in another collection · chain A against A, TM-score 1.00
- Q9HBL8 · AlphaFold monomer V2.0 prediction for nmra-like family domain- containing protein 1… · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9HBL8
- Elsewhere: RCSB PDB 2WM3 · PDBe 2WM3 · UniProt Q9HBL8
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