Research workbench
Crystal structure of the tyrosine phosphatase CPS4B from steptococcus pneumoniae TIGR4 in complex with phosphate.
Analyse Crystal structure of the tyrosine phosphatase CPS4B from steptococcus… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2WJF
- Type
- protein
- Length
- 244 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Tyrosine-protein phosphatase cpsb
- EC
- 3.1.3.48
- UniProt
- Q9AHD4
- Ligands
- MN, PO4
- Pockets
- 2 · best druggability 0.44
Structure
x-ray diffraction · 1 distinct chain · 46% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Tyrosine-protein phosphatase cpsb (EC 3.1.3.48) | protein | 244 | 46% helix, 16% strand | Q9AHD4 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 135 | 0.44 | 0.77 | 22 | empty |
| 2 | 62 | 0.39 | 0.80 | 17 | empty |
Compared structures
- 2WJF · Crystal structure of the tyrosine phosphatase Cps4B from Steptococcus pneumoniae TIGR4 in… · the same entry in another collection · chain A against A, TM-score 1.00
- Q9AHD4 · AlphaFold monomer V2.0 prediction for tyrosine-protein phosphatase cpsb (Q9AHD4) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9AHD4
- Elsewhere: RCSB PDB 2WJF · PDBe 2WJF · UniProt Q9AHD4
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